Tablet Presentation

Each Film Coated Modified Release Tablet Contains:
Tamsulosin Hydrochloride IP 0.4 mg

Tamsulosin is the sympatholytic drugs, it selectively blocks the alpha-1 and alpha-2 antagonist , Blockage of these receptors in the smooth muscles promotes relaxation of the smooth muscles of the bladder.

Indication

• Prostatic hypertrophy
• Promotes hypotension
• Prostatitis
• Ureteral stones

Mechanism of Action:

It acts in the alpha-1 & 2 receptors and blocks it action therefore relaxes the smooth muscles in the prostate gland and detrusor muscle in the bladder, improves the flow of urine.

Pharmacokinetics

Absorption- It is rapidly absorbed from the git
Protein binding- It is about 98% bound to alpha acid -1 glycoprotein
Metabolism- It undergoes sulphate conjugation
Excretion- It is excreted via urine

Side Effects

• Nausea
• Vomiting
• Blurring of vision
• Back pain
• Dizziness
• Drowsiness

Contraindication

• Contraindicated in patients with known hypersensitivity
• Contraindicated in pregnancy
• Contraindicated in patients with liver problems

Storage

Store this drug at room temperature